General Cell Based Assays
Revvity Health Sciences Inc HTRF Human & Mouse Total IRS2 Detection Kit, 500 Assay Points
HTRF Human & Mouse Total IRS2 Detection Kit, 500 Assay Points
Revvity Health Sciences Inc HTRF Human & Mouse Total Histone H3 Detection Kit, 10,000 Assay Points
HTRF Human & Mouse Total Histone H3 Detection Kit, 10,000 Assay Points
Montana Molecular Human Somatostatin Receptor Type 2 (SSTR2) Big Sky BacMam, 15mL
Human Somatostatin Receptor Type 2 packaged in Big Sky BacMam for mammalian cell expression. BacMam packaging provides efficient transduction in most cell types - including uniform and near 100% efficiency in HEK293 cells as well as expression in primary or iPSC-derived cells. BacMam expression is easily titrateable to suit your experimental needs.
Meso Scale Discovery U-PLEX Human DPPIV ASY
The Meso Scale Discovery U-PLEX Human DPP4 Assay Kit is a multiplex immunoassay that measures Dipeptidyl Peptidase 4 (DPP4) levels in human serum plasma and cell culture supernatants This assay utilizes electrochemiluminescence (ECL) detection technology and provides high sensitivity broad dynamic range and rapid results The kit includes a 96-well plate pre-coated with capture antibody detection antibody read buffer calibrator and controls Sample incubation time is 2 hours and total assay time is 3 5 hours The assay is designed for the quantitative measurement of DPP4 levels for life science research applications
Eurofins Discoverx PathHunter eXpress ADCYAP1R1 Total Internalization Assay, 2pl Kit. (93-0885E3CP0M)
The PathHunter ADCYAP1R1 Total Internalization eXpress kit provides an easy to-use cell based assay to study drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This kit uses EFC technology to measure ligand-induced internalization of ADCYAP1R1 via detection of localization to the early endosome. The included cell line overexpresses ProLink-tagged ADCYAP1R1 and an EA-tagged early endosome protein. Upon ligand-induced receptor activation, resulting internalization of the ADCYAP1R1 receptor to the early endosome leads to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter Human MIP-3β (CCRL1) β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human MIP-3β (CCRL1) β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure CCRL1 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx InCELL Hunter eXpress SIK1 Kinase Binding Assay, 2pl Kit. (96-0051E15CP0M)
The InCELL Hunter eXpress SIK1 Kinase Binding Assay provides an easy-to-use cell based assay to study small molecule drug candidates that engage with kinases. This kit assesses compound-engagement-based stabilization of SIK1 via detection of SIK1 levels. This product uses EFC technology. The cell line included overexpresses SIK1 target protein fused to ProLabel. In the absence of compound that binds and stabilizes the target, this protein is degraded and no EFC signal is produced. When compound engages and stabilizes the target, EA contained in the detection reagent produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress LGR5 CHO-K1 β-Arrestin Orphan GPCR Assay, 2-Plate Kit. (93-0526E2ACP1M)
The PathHunter LGR5 (GPR49) eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. R-spondins) based activation of LGR5 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged LGR5 and EA-tagged β-Arrestin-2. Activation of LGR5 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Abcam CDC, lipo x ygenase inhibitor, 50MG
MW 321.3 g/mol, Purity >98%. Potent, selective 12-Lipoxygenase (12-LO) inhibitor (IC₅₀ = 63 nM). Also inhibits 15-LO and 5-LO (IC₅₀ values are 3.33 and 1.89 μM respectively). Active in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Meso Scale Discovery R-PLEX Mouse IL-7 ASY
The R-PLEX Mouse IL-7 Assay from Meso Scale Discovery is a multiplex immunoassay for measuring mouse interleukin 7 (IL-7) in serum plasma and cell culture supernatants It uses electrochemiluminescence (ECL) detection offering high sensitivity a dynamic range of up to 5 logs and low sample volume needs It quantifies IL-7 from 0 05 to 10 000 pg/mL with just 25 L of sample The kit includes a 96-well plate with capture antibodies ECL-tagged detection antibodies calibrators diluent wash buffer read buffer and plate seals ensuring rapid and reliable IL-7 quantification
Eurofins Discoverx PathHunter Human BDKRB2 β-Arrestin Cell-Based Assay Kit (HEK 293)
The PathHunter Human BDKRB2 β-Arrestin Stable Cell Line Assay (HEK 293) contains a stable clonal cell line used to measure BDKRB2 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Meso Scale Discovery RPLEX NHP Alphaamylase 2A ASY
The R-Plex NHP Alpha-Amylase 2A Assay Kit from Meso Scale Discovery is a 96-well electrochemiluminescent immunoassay for the quantitative measurement of alpha-amylase 2A in human serum plasma saliva and cell culture supernatants The assay uses MSD GOLD SULFO-TAG labels and has a typical sensitivity of 0 04 ng/mL with an assay range of 0 1-400 ng/mL The kit includes a 96-well MULTI-ARRAY Human Alpha-Amylase 2A Plate SULFO-TAG Anti-Alpha-Amylase 2A Antibody Sample Diluent Read Buffer T (4X) and validations packet This assay allows for high-throughput sensitive and accurate quantification of alpha-amylase 2A levels
Eurofins Discoverx PathHunter Human P2RY6 β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human P2RY6 β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure P2RY6 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Meso Scale Discovery R-PLEX Rat IL-13 ASY
The R-PLEX Rat IL-13 Assay from Meso Scale Diagnostics is a multiplex immunoassay that measures rat interleukin 13 (IL-13) in serum plasma and cell culture supernatants This assay uses electrochemiluminescence (ECL) detection technology and provides high sensitivity broad dynamic range and requires low sample volume The assay has high specificity and shows minimal cross-reactivity The kit includes a 96-well plate coated with capture antibody detection antibody read buffer wash buffer blocker reagents and calibrator The assay takes 3 5 hours to complete and has a sensitivity of 0 3 pg/mL
Eurofins Discoverx PathHunter eXpress MC3R U2OS β-Arrestin GPCR Assay, 10-Plate Kit. (93-0984E3CP5L)
The PathHunter MC3R eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. α-MSH) based activation of MC3R GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged MC3R and EA-tagged β-Arrestin-2. Activation of MC3R stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.